calculate_a_optimality

obsidian.experiment.advanced_design.calculate_a_optimality(design, continuous_params_keys, subparam_keys)

Calculate A-optimality (trace of the inverse information matrix) for the continuous and subparameter columns.

Parameters:

• design – Design DataFrame.

• continuous_params_keys – List of continuous parameter column names.

• subparam_keys – List of subparameter column names, or a single string.

Returns:

Trace of (X^T X)^{-1} (lower is better).

Return type:

float